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| Air Date | Show Name | Epis# | Episode Title |
|---|---|---|---|
| Season 1 | |||
| 14-Sep-2020 | The Drew Barrymore Show | S01E01 | Adam Sandler |
| 15-Sep-2020 | The Drew Barrymore Show | S01E02 | Reese Witherspoon |
| 16-Sep-2020 | The Drew Barrymore Show | S01E03 | Jane Fonda |
| 17-Sep-2020 | The Drew Barrymore Show | S01E04 | Jonah Larson |
| 18-Sep-2020 | The Drew Barrymore Show | S01E05 | Billy Porter |
| 21-Sep-2020 | The Drew Barrymore Show | S01E06 | Paris Hilton |
| 22-Sep-2020 | The Drew Barrymore Show | S01E07 | Gwyneth Paltrow |
| 23-Sep-2020 | The Drew Barrymore Show | S01E08 | Stephen Colbert |
| 24-Sep-2020 | The Drew Barrymore Show | S01E09 | Rosario Dawson |
| 25-Sep-2020 | The Drew Barrymore Show | S01E10 | Tom Green |
| 28-Sep-2020 | The Drew Barrymore Show | S01E11 | Julianne Moore |
| 29-Sep-2020 | The Drew Barrymore Show | S01E12 | Savannah Guthrie |
| 30-Sep-2020 | The Drew Barrymore Show | S01E13 | Nicole Richie |
| 01-Oct-2020 | The Drew Barrymore Show | S01E14 | Andrew Rannells |
| 02-Oct-2020 | The Drew Barrymore Show | S01E15 | Jason Sudeikis |
| 05-Oct-2020 | The Drew Barrymore Show | S01E16 | Phoebe Robinson |
| 06-Oct-2020 | The Drew Barrymore Show | S01E17 | Jane Lynch |
| 07-Oct-2020 | The Drew Barrymore Show | S01E18 | Jonathan Van Ness |
| 08-Oct-2020 | The Drew Barrymore Show | S01E19 | Kathie Lee Gifford |
| 09-Oct-2020 | The Drew Barrymore Show | S01E20 | James Corden |
| 12-Oct-2020 | The Drew Barrymore Show | S01E21 | Jessica Alba |
| 13-Oct-2020 | The Drew Barrymore Show | S01E22 | Gloria Estefan |
| 14-Oct-2020 | The Drew Barrymore Show | S01E23 | Sharon Stone |
| 15-Oct-2020 | The Drew Barrymore Show | S01E24 | Henry Winkler |
| 16-Oct-2020 | The Drew Barrymore Show | S01E25 | Hoda Kotb |
| 19-Oct-2020 | The Drew Barrymore Show | S01E26 | Rachael Ray |
| 20-Oct-2020 | The Drew Barrymore Show | S01E27 | June Diane Raphael |
| 21-Oct-2020 | The Drew Barrymore Show | S01E28 | Glennon Doyle |
| 22-Oct-2020 | The Drew Barrymore Show | S01E29 | Karamo Brown |
| 23-Oct-2020 | The Drew Barrymore Show | S01E30 | Seth MacFarlane |
| 26-Oct-2020 | The Drew Barrymore Show | S01E31 | Adam Sandler |
| 27-Oct-2020 | The Drew Barrymore Show | S01E32 | Stanley Tucci |
| 28-Oct-2020 | The Drew Barrymore Show | S01E33 | Dr. Phil |
| 29-Oct-2020 | The Drew Barrymore Show | S01E34 | Anne Hathaway |
| 30-Oct-2020 | The Drew Barrymore Show | S01E35 | Ashley Park |
| 02-Nov-2020 | The Drew Barrymore Show | S01E36 | Chelsea Handler |
| 03-Nov-2020 | The Drew Barrymore Show | S01E37 | Jessica Capshaw |
| 04-Nov-2020 | The Drew Barrymore Show | S01E38 | David Dobrik |
| 05-Nov-2020 | The Drew Barrymore Show | S01E39 | Gabriel Iglesias |
| 06-Nov-2020 | The Drew Barrymore Show | S01E40 | Winnie Harlow |
| 09-Nov-2020 | The Drew Barrymore Show | S01E41 | Zooey Deschanel |
| 10-Nov-2020 | The Drew Barrymore Show | S01E42 | Rebel Wilson |
| 11-Nov-2020 | The Drew Barrymore Show | S01E43 | Milo Ventimiglia |
| 12-Nov-2020 | The Drew Barrymore Show | S01E44 | Chris O'Donnell |
| 13-Nov-2020 | The Drew Barrymore Show | S01E45 | Emma Roberts |
| 16-Nov-2020 | The Drew Barrymore Show | S01E46 | Iman |
| 17-Nov-2020 | The Drew Barrymore Show | S01E47 | Michael Strahan |
| 18-Nov-2020 | The Drew Barrymore Show | S01E48 | Megan Rapinoe |
| 19-Nov-2020 | The Drew Barrymore Show | S01E49 | Liza Koshy |
| 20-Nov-2020 | The Drew Barrymore Show | S01E50 | Miranda Kerr |
| 23-Nov-2020 | The Drew Barrymore Show | S01E51 | Annaleigh Ashford |
| 24-Nov-2020 | The Drew Barrymore Show | S01E52 | Kay and Camila McConaughey |
| 25-Nov-2020 | The Drew Barrymore Show | S01E53 | Kelly Rowland |
| 30-Nov-2020 | The Drew Barrymore Show | S01E54 | Hunter McGrady |
| 01-Dec-2020 | The Drew Barrymore Show | S01E55 | Gordon Ramsay |
| 02-Dec-2020 | The Drew Barrymore Show | S01E56 | Jenny Slate |
| 03-Dec-2020 | The Drew Barrymore Show | S01E57 | Jennifer Garner |
| 04-Dec-2020 | The Drew Barrymore Show | S01E58 | Martha Stewart |
| 07-Dec-2020 | The Drew Barrymore Show | S01E59 | Jimmy Fallon |
| 08-Dec-2020 | The Drew Barrymore Show | S01E60 | Ken Jeong |
| 09-Dec-2020 | The Drew Barrymore Show | S01E61 | Neil Patrick Harris |
| 10-Dec-2020 | The Drew Barrymore Show | S01E62 | Ellie Kemper |
| 11-Dec-2020 | The Drew Barrymore Show | S01E63 | Kristen Bell |
| 14-Dec-2020 | The Drew Barrymore Show | S01E64 | Elaine Welteroth |
| 15-Dec-2020 | The Drew Barrymore Show | S01E65 | Zosia Mamet |
| 16-Dec-2020 | The Drew Barrymore Show | S01E66 | Joe Manganiello |
| 17-Dec-2020 | The Drew Barrymore Show | S01E67 | Natalie Portman |
| 21-Dec-2020 | The Drew Barrymore Show | S01E68 | Kate Mara |
| 04-Jan-2021 | The Drew Barrymore Show | S01E69 | Nikki Glaser |
| 05-Jan-2021 | The Drew Barrymore Show | S01E70 | Judge Marilyn Milian |
| 06-Jan-2021 | The Drew Barrymore Show | S01E71 | Charlize Theron |
| 07-Jan-2021 | The Drew Barrymore Show | S01E72 | Danny Seo |
| 08-Jan-2021 | The Drew Barrymore Show | S01E73 | Karamo Brown |
| 11-Jan-2021 | The Drew Barrymore Show | S01E74 | Craig Ferguson |
| 12-Jan-2021 | The Drew Barrymore Show | S01E75 | Carrie Underwood |
| 13-Jan-2021 | The Drew Barrymore Show | S01E76 | Jane Krakowski |
| 14-Jan-2021 | The Drew Barrymore Show | S01E77 | Meagan Good |
| 15-Jan-2021 | The Drew Barrymore Show | S01E78 | Ralph Macchio |
| 18-Jan-2021 | The Drew Barrymore Show | S01E79 | Danny Seo |
| 19-Jan-2021 | The Drew Barrymore Show | S01E80 | Cole Sprouse |
| 20-Jan-2021 | The Drew Barrymore Show | S01E81 | Karamo Brown |
| 21-Jan-2021 | The Drew Barrymore Show | S01E82 | Kat Graham |
| 22-Jan-2021 | The Drew Barrymore Show | S01E83 | Taye Diggs |
| 25-Jan-2021 | The Drew Barrymore Show | S01E84 | Dakota Johnson |
| 26-Jan-2021 | The Drew Barrymore Show | S01E85 | Matthew McConaughey |
| 27-Jan-2021 | The Drew Barrymore Show | S01E86 | Drew Carey |
| 28-Jan-2021 | The Drew Barrymore Show | S01E87 | Wayne Brady |
| 29-Jan-2021 | The Drew Barrymore Show | S01E88 | Leah Remini |
| 01-Feb-2021 | The Drew Barrymore Show | S01E89 | Jameela Jamil |
| 02-Feb-2021 | The Drew Barrymore Show | S01E90 | Lilly Singh |
| 03-Feb-2021 | The Drew Barrymore Show | S01E91 | The Talk |
| 04-Feb-2021 | The Drew Barrymore Show | S01E92 | Josh Lucas |
| 05-Feb-2021 | The Drew Barrymore Show | S01E93 | Rachael Ray |
| 08-Feb-2021 | The Drew Barrymore Show | S01E94 | Patti LaBelle |
| 09-Feb-2021 | The Drew Barrymore Show | S01E95 | Katherine Heigl |
| 10-Feb-2021 | The Drew Barrymore Show | S01E96 | Lionel Richie |
| 11-Feb-2021 | The Drew Barrymore Show | S01E97 | Giada De Laurentiis |
| 12-Feb-2021 | The Drew Barrymore Show | S01E98 | Lana Condor |
| 16-Feb-2021 | The Drew Barrymore Show | S01E99 | Ricki Lake |
| 17-Feb-2021 | The Drew Barrymore Show | S01E100 | Jennifer Love Hewitt |
| 18-Feb-2021 | The Drew Barrymore Show | S01E101 | Kat Dennings |
| 19-Feb-2021 | The Drew Barrymore Show | S01E102 | Jason Biggs |
| 22-Feb-2021 | The Drew Barrymore Show | S01E103 | David Letterman |
| 23-Feb-2021 | The Drew Barrymore Show | S01E104 | Kristen Wiig |
| 24-Feb-2021 | The Drew Barrymore Show | S01E105 | Ben Platt |
| 25-Feb-2021 | The Drew Barrymore Show | S01E106 | Andra Day |
| 26-Feb-2021 | The Drew Barrymore Show | S01E107 | Chloë Grace Moretz |
| 01-Mar-2021 | The Drew Barrymore Show | S01E108 | Leslie Mann |
| 02-Mar-2021 | The Drew Barrymore Show | S01E109 | Dr. Oz |
| 03-Mar-2021 | The Drew Barrymore Show | S01E110 | Stephen King |
| 04-Mar-2021 | The Drew Barrymore Show | S01E111 | Kelly Marie Tran |
| 05-Mar-2021 | The Drew Barrymore Show | S01E112 | Zach Braff |
| 08-Mar-2021 | The Drew Barrymore Show | S01E113 | Diane von Furstenberg |
| 09-Mar-2021 | The Drew Barrymore Show | S01E114 | Oliver Hudson |
| 10-Mar-2021 | The Drew Barrymore Show | S01E115 | Ike Barinholtz |
| 11-Mar-2021 | The Drew Barrymore Show | S01E116 | Phil Donahue |
| 12-Mar-2021 | The Drew Barrymore Show | S01E117 | Eddie Murphy |
| 15-Mar-2021 | The Drew Barrymore Show | S01E118 | Idina Menzel |
| 16-Mar-2021 | The Drew Barrymore Show | S01E119 | Anthony Anderson and Doris Bowman |
| 17-Mar-2021 | The Drew Barrymore Show | S01E120 | Lamorne Morris |
| 18-Mar-2021 | The Drew Barrymore Show | S01E121 | Mayim Bialik |
| 19-Mar-2021 | The Drew Barrymore Show | S01E122 | Nick Offerman |
| 22-Mar-2021 | The Drew Barrymore Show | S01E123 | Joel McHale |
| 23-Mar-2021 | The Drew Barrymore Show | S01E124 | Alyson Hannigan |
| 24-Mar-2021 | The Drew Barrymore Show | S01E125 | Sara Gilbert |
| 25-Mar-2021 | The Drew Barrymore Show | S01E126 | Khloe Kardashian |
| 26-Mar-2021 | The Drew Barrymore Show | S01E127 | Edgar Ramirez |
| 29-Mar-2021 | The Drew Barrymore Show | S01E128 | Giada De Laurentiis |
| 30-Mar-2021 | The Drew Barrymore Show | S01E129 | Jesse Tyler Ferguson |
| 31-Mar-2021 | The Drew Barrymore Show | S01E130 | Kenan Thompson |
| 01-Apr-2021 | The Drew Barrymore Show | S01E131 | Seth Meyers |
| 02-Apr-2021 | The Drew Barrymore Show | S01E132 | Chris Jackson |
| 05-Apr-2021 | The Drew Barrymore Show | S01E133 | Brené Brown |
| 06-Apr-2021 | The Drew Barrymore Show | S01E134 | Allison Janney |
| 07-Apr-2021 | The Drew Barrymore Show | S01E135 | Lee Daniels |
| 08-Apr-2021 | The Drew Barrymore Show | S01E136 | Josh Groban |
| 09-Apr-2021 | The Drew Barrymore Show | S01E137 | Bobby Flay |
| 12-Apr-2021 | The Drew Barrymore Show | S01E138 | Lena Dunham |
| 13-Apr-2021 | The Drew Barrymore Show | S01E139 | Demi Lovato |
| 14-Apr-2021 | The Drew Barrymore Show | S01E140 | Kyra Sedgwick |
| 15-Apr-2021 | The Drew Barrymore Show | S01E141 | Sutton Foster |
| 16-Apr-2021 | The Drew Barrymore Show | S01E142 | Tom Selleck |
| 19-Apr-2021 | The Drew Barrymore Show | S01E143 | Terry and Rebecca Crews |
| 20-Apr-2021 | The Drew Barrymore Show | S01E144 | Jenny McCarthy |
| 21-Apr-2021 | The Drew Barrymore Show | S01E145 | Willie Geist |
| 22-Apr-2021 | The Drew Barrymore Show | S01E146 | Neil deGrasse Tyson |
| 23-Apr-2021 | The Drew Barrymore Show | S01E147 | Kevin Frazier |
| 26-Apr-2021 | The Drew Barrymore Show | S01E148 | Sarah Chalke |
| 27-Apr-2021 | The Drew Barrymore Show | S01E149 | Jason Derulo |
| 28-Apr-2021 | The Drew Barrymore Show | S01E150 | Kevin Bacon |
| 29-Apr-2021 | The Drew Barrymore Show | S01E151 | Jessica Simpson |
| 30-Apr-2021 | The Drew Barrymore Show | S01E152 | Oprah Winfrey |
| 03-May-2021 | The Drew Barrymore Show | S01E153 | Katey Sagal |
| 04-May-2021 | The Drew Barrymore Show | S01E154 | Catherine Zeta Jones |
| 05-May-2021 | The Drew Barrymore Show | S01E155 | Laura Prepon |
| 06-May-2021 | The Drew Barrymore Show | S01E156 | Patricia Heaton |
| 07-May-2021 | The Drew Barrymore Show | S01E157 | Vanessa Hudgens |
| 10-May-2021 | The Drew Barrymore Show | S01E158 | David Oyelowo |
| 11-May-2021 | The Drew Barrymore Show | S01E159 | Courteney Cox |
| 12-May-2021 | The Drew Barrymore Show | S01E160 | Girls5eva |
| 13-May-2021 | The Drew Barrymore Show | S01E161 | Julianna Margulies |
| 14-May-2021 | The Drew Barrymore Show | S01E162 | Adam Sandler |
| 17-May-2021 | The Drew Barrymore Show | S01E163 | Dylan Farrow |
| 18-May-2021 | The Drew Barrymore Show | S01E164 | Jason Momoa |
| 19-May-2021 | The Drew Barrymore Show | S01E165 | Nina Dobrev and Julianne Hough |
| 20-May-2021 | The Drew Barrymore Show | S01E166 | Hugh Grant |
| 21-May-2021 | The Drew Barrymore Show | S01E167 | Anne Hathaway |
| 24-May-2021 | The Drew Barrymore Show | S01E168 | Best of Female Ground Breakers |
| 25-May-2021 | The Drew Barrymore Show | S01E169 | Best of Lifestyle Segments |
| 26-May-2021 | The Drew Barrymore Show | S01E170 | Best of Beauty Hour |
| 27-May-2021 | The Drew Barrymore Show | S01E171 | Best of Co-Stars |
| 28-May-2021 | The Drew Barrymore Show | S01E172 | Best of Surprises |
| Season 2 | |||
| 13-Sep-2021 | The Drew Barrymore Show | S02E01 | Jennifer Aniston |
| 14-Sep-2021 | The Drew Barrymore Show | S02E02 | Molly Shannon |
| 15-Sep-2021 | The Drew Barrymore Show | S02E03 | Cameron Diaz |
| 16-Sep-2021 | The Drew Barrymore Show | S02E04 | Billie Eilish |
| 17-Sep-2021 | The Drew Barrymore Show | S02E05 | Cedric the Entertainer |
| 20-Sep-2021 | The Drew Barrymore Show | S02E06 | Awkwafina |
| 21-Sep-2021 | The Drew Barrymore Show | S02E07 | Carmelo Anthony |
| 22-Sep-2021 | The Drew Barrymore Show | S02E08 | John Stamos |
| 23-Sep-2021 | The Drew Barrymore Show | S02E09 | Martha Stewart |
| 24-Sep-2021 | The Drew Barrymore Show | S02E10 | Ben Platt |
| 27-Sep-2021 | The Drew Barrymore Show | S02E11 | Zanna Roberts Rassi |
| 28-Sep-2021 | The Drew Barrymore Show | S02E12 | Vanessa Hudgens |
| 29-Sep-2021 | The Drew Barrymore Show | S02E13 | Padma Lakshmi |
| 30-Sep-2021 | The Drew Barrymore Show | S02E14 | Elmo |
| 01-Oct-2021 | The Drew Barrymore Show | S02E15 | Phoebe Robinson |
| 04-Oct-2021 | The Drew Barrymore Show | S02E16 | Bobby Flay |
| 05-Oct-2021 | The Drew Barrymore Show | S02E17 | 50 Cent |
| 06-Oct-2021 | The Drew Barrymore Show | S02E18 | Jason Biggs |
| 07-Oct-2021 | The Drew Barrymore Show | S02E19 | Dakota Johnson |
| 08-Oct-2021 | The Drew Barrymore Show | S02E20 | The Estefans |
| 11-Oct-2021 | The Drew Barrymore Show | S02E21 | Adam Lambert |
| 12-Oct-2021 | The Drew Barrymore Show | S02E22 | Ike Barinholtz |
| 13-Oct-2021 | The Drew Barrymore Show | S02E23 | Chelsea Handler |
| 14-Oct-2021 | The Drew Barrymore Show | S02E24 | Meridith Hagner |
| 15-Oct-2021 | The Drew Barrymore Show | S02E25 | Heather Locklear |
| 18-Oct-2021 | The Drew Barrymore Show | S02E26 | Scott Speedman |
| 19-Oct-2021 | The Drew Barrymore Show | S02E27 | Alicia Silverstone |
| 20-Oct-2021 | The Drew Barrymore Show | S02E28 | Ron Howard |
| 21-Oct-2021 | The Drew Barrymore Show | S02E29 | Leslie Grossman |
| 22-Oct-2021 | The Drew Barrymore Show | S02E30 | Gwyneth Paltrow |
| 25-Oct-2021 | The Drew Barrymore Show | S02E31 | Jaleel White |
| 26-Oct-2021 | The Drew Barrymore Show | S02E32 | Tom Green |
| 27-Oct-2021 | The Drew Barrymore Show | S02E33 | Alyssa Milano |
| 28-Oct-2021 | The Drew Barrymore Show | S02E34 | Rachael Ray |
| 29-Oct-2021 | The Drew Barrymore Show | S02E35 | Ross Mathews |
| 01-Nov-2021 | The Drew Barrymore Show | S02E36 | Anderson Cooper |
| 02-Nov-2021 | The Drew Barrymore Show | S02E37 | Alex Cooper |
| 03-Nov-2021 | The Drew Barrymore Show | S02E38 | Kristen Bell, Dax Shepard |
| 04-Nov-2021 | The Drew Barrymore Show | S02E39 | Annaleigh Ashford |
| 05-Nov-2021 | The Drew Barrymore Show | S02E40 | Billy Porter |
| 08-Nov-2021 | The Drew Barrymore Show | S02E41 | Michelle Pfeiffer, Katie Sturino |
| 09-Nov-2021 | The Drew Barrymore Show | S02E42 | Casey Wilson |
| 10-Nov-2021 | The Drew Barrymore Show | S02E43 | Emily Ratajkowski, Jenny McCarthy |
| 11-Nov-2021 | The Drew Barrymore Show | S02E44 | Andy Cohen, Zazie Beetz |
| 12-Nov-2021 | The Drew Barrymore Show | S02E45 | Keke Palmer, Addison Rae |
| 15-Nov-2021 | The Drew Barrymore Show | S02E46 | America Ferrera |
| 16-Nov-2021 | The Drew Barrymore Show | S02E47 | Jeff Goldblum |
| 17-Nov-2021 | The Drew Barrymore Show | S02E48 | Jenny McCarthy |
| 18-Nov-2021 | The Drew Barrymore Show | S02E49 | Gayle King |
| 19-Nov-2021 | The Drew Barrymore Show | S02E50 | Bella Twins |
| 22-Nov-2021 | The Drew Barrymore Show | S02E51 | Charlamagne Tha God |
| 23-Nov-2021 | The Drew Barrymore Show | S02E52 | Hailee Steinfeld |
| 29-Nov-2021 | The Drew Barrymore Show | S02E53 | Kathryn Hahn |
| 30-Nov-2021 | The Drew Barrymore Show | S02E54 | Brooke Shields |
| 01-Dec-2021 | The Drew Barrymore Show | S02E55 | Dionne Warwick |
| 02-Dec-2021 | The Drew Barrymore Show | S02E56 | Vanessa Williams |
| 03-Dec-2021 | The Drew Barrymore Show | S02E57 | Kal Penn |
| 06-Dec-2021 | The Drew Barrymore Show | S02E58 | Ansel Elgort |
| 07-Dec-2021 | The Drew Barrymore Show | S02E59 | Whoopi Goldberg |
| 08-Dec-2021 | The Drew Barrymore Show | S02E60 | Kristin Chenoweth |
| 09-Dec-2021 | The Drew Barrymore Show | S02E61 | Ariana DeBose |
| 10-Dec-2021 | The Drew Barrymore Show | S02E62 | Machine Gun Kelly |
| 13-Dec-2021 | The Drew Barrymore Show | S02E63 | Maya Erskine & Anna Konkle |
| 14-Dec-2021 | The Drew Barrymore Show | S02E64 | Kristin Davis |
| 15-Dec-2021 | The Drew Barrymore Show | S02E65 | Jonathan Groff |
| 16-Dec-2021 | The Drew Barrymore Show | S02E66 | Aubrey Plaza |
| 17-Dec-2021 | The Drew Barrymore Show | S02E67 | Chelsea Handler |
| 20-Dec-2021 | The Drew Barrymore Show | S02E68 | Kendrick Sampson |
| 21-Dec-2021 | The Drew Barrymore Show | S02E69 | Keanu Reeves |
| 22-Dec-2021 | The Drew Barrymore Show | S02E70 | Reese Witherspoon |
| 10-Jan-2022 | The Drew Barrymore Show | S02E71 | Courteney Cox |
| 11-Jan-2022 | The Drew Barrymore Show | S02E72 | Fred Savage |
| 12-Jan-2022 | The Drew Barrymore Show | S02E73 | Dylan Minnette |
| 13-Jan-2022 | The Drew Barrymore Show | S02E74 | Jonathan Van Ness |
| 14-Jan-2022 | The Drew Barrymore Show | S02E75 | Ava Duvernay |
| 17-Jan-2022 | The Drew Barrymore Show | S02E76 | John Cena |
| 18-Jan-2022 | The Drew Barrymore Show | S02E77 | Mariska Hargitay |
| 19-Jan-2022 | The Drew Barrymore Show | S02E78 | Ginnifer Goodwin, Maggie Q, & Eliza Coupe |
| 20-Jan-2022 | The Drew Barrymore Show | S02E79 | Kyle Mooney |
| 21-Jan-2022 | The Drew Barrymore Show | S02E80 | Valerie Bertinelli |
| 24-Jan-2022 | The Drew Barrymore Show | S02E81 | Sarita Choudhury |
| 25-Jan-2022 | The Drew Barrymore Show | S02E82 | Huma Abedin |
| 26-Jan-2022 | The Drew Barrymore Show | S02E83 | Cynthia Nixon |
| 27-Jan-2022 | The Drew Barrymore Show | S02E84 | Kate Hudson |
| 28-Jan-2022 | The Drew Barrymore Show | S02E85 | Paris Hilton |
| 31-Jan-2022 | The Drew Barrymore Show | S02E86 | Sheila E |
| 01-Feb-2022 | The Drew Barrymore Show | S02E87 | Savannah Guthrie |
| 02-Feb-2022 | The Drew Barrymore Show | S02E88 | 50 Cent |
| 03-Feb-2022 | The Drew Barrymore Show | S02E89 | Ike Barinholtz |
| 04-Feb-2022 | The Drew Barrymore Show | S02E90 | Johnny Knoxville |
| 07-Feb-2022 | The Drew Barrymore Show | S02E91 | Nicole Byer; Chef Edy Massih |
| 08-Feb-2022 | The Drew Barrymore Show | S02E92 | Sam Richardson |
| 10-Feb-2022 | The Drew Barrymore Show | S02E93 | Sterling K. Brown; Joey King |
| 11-Feb-2022 | The Drew Barrymore Show | S02E94 | "I Want You Back" Cast |
| 14-Feb-2022 | The Drew Barrymore Show | S02E95 | Valentine's Day Show - Gayle King; Taye Diggs |
| 15-Feb-2022 | The Drew Barrymore Show | S02E96 | Michael Zegen |
| 17-Feb-2022 | The Drew Barrymore Show | S02E97 | Drew's Crew to the Rescue Hour |
| 18-Feb-2022 | The Drew Barrymore Show | S02E98 | Drew-Gooder |
| 21-Feb-2022 | The Drew Barrymore Show | S02E99 | Kat Dennings |
| 22-Feb-2022 | The Drew Barrymore Show | S02E100 | Drew's Big Birthday Bash! - Rachel Dratch; Ana Gasteyer; The Go-Go's |
| 23-Feb-2022 | The Drew Barrymore Show | S02E101 | Hannah Waddingham |
| 24-Feb-2022 | The Drew Barrymore Show | S02E102 | Casey Wilson & Danielle Schneider; Wildflower; Haley Bennett |
| 25-Feb-2022 | The Drew Barrymore Show | S02E103 | Sophia Bush |
| 28-Feb-2022 | The Drew Barrymore Show | S02E104 | Joseph Gordon-Levitt; Morena Baccarin |
| 01-Mar-2022 | The Drew Barrymore Show | S02E105 | Candace Bushnell; Mark Cuban |
| 02-Mar-2022 | The Drew Barrymore Show | S02E106 | Anna Chlumsky; Aida Rodriguez |
| 03-Mar-2022 | The Drew Barrymore Show | S02E107 | Drew's News; Eitan Nutella Ravioli |
| 04-Mar-2022 | The Drew Barrymore Show | S02E108 | Sabrina Carpenter |
| 07-Mar-2022 | The Drew Barrymore Show | S02E109 | Greg Kinnear |
| 09-Feb-2022 | The Drew Barrymore Show | S02E110 | Ilana Glazer; Deborah Norville |
| 16-Feb-2022 | The Drew Barrymore Show | S02E111 | The Colorful Hour |
| 08-Mar-2022 | The Drew Barrymore Show | S02E112 | Taylor Schilling |
| 09-Mar-2022 | The Drew Barrymore Show | S02E113 | Sam Heughan |
| 10-Mar-2022 | The Drew Barrymore Show | S02E114 | Topher Grace; HGTV Stars Mike Jackson & Egypt Sherrod |
| 11-Mar-2022 | The Drew Barrymore Show | S02E115 | Michelle Buteau |
| 14-Mar-2022 | The Drew Barrymore Show | S02E116 | Adam Scott |
| 15-Mar-2022 | The Drew Barrymore Show | S02E117 | Eric Stonestreet |
| 16-Mar-2022 | The Drew Barrymore Show | S02E118 | Scarlett Johansson |
| 17-Mar-2022 | The Drew Barrymore Show | S02E119 | Evan Rachel Wood; Debbie Gibson |
| 18-Mar-2022 | The Drew Barrymore Show | S02E120 | Seth Meyers; Britt Lower |
| 21-Mar-2022 | The Drew Barrymore Show | S02E121 | Nicola Coughlan |
| 22-Mar-2022 | The Drew Barrymore Show | S02E122 | Troy Kotsur & Marlee Matli |
| 23-Mar-2022 | The Drew Barrymore Show | S02E123 | Gabrielle Union, Molly Sims |
| 24-Mar-2022 | The Drew Barrymore Show | S02E124 | Amy Schumer and Violet Young; Olivia Rodrigo |
| 25-Mar-2022 | The Drew Barrymore Show | S02E125 | John Cho; Iris Apatow |
| 18-Apr-2022 | The Drew Barrymore Show | S02E126 | Dee Wallace |
| 19-Apr-2022 | The Drew Barrymore Show | S02E127 | Claire Foy |
| 20-Apr-2022 | The Drew Barrymore Show | S02E128 | Mary-Louise Parker |
| 21-Apr-2022 | The Drew Barrymore Show | S02E129 | Ben Schwartz |
| 22-Apr-2022 | The Drew Barrymore Show | S02E130 | Neil deGrasse Tyson; Naomie Harris; June Diane Raphael |
| Season 3 | |||
| 12-Sep-2022 | The Drew Barrymore Show | S03E01 | Justin Long |
| 13-Sep-2022 | The Drew Barrymore Show | S03E02 | Katy Perry |
| 14-Sep-2022 | The Drew Barrymore Show | S03E03 | Selma Blair |
| 15-Sep-2022 | The Drew Barrymore Show | S03E04 | Hillary and Chelsea Clinton |
| 16-Sep-2022 | The Drew Barrymore Show | S03E05 | Idris and Sabrina Elba |
| 19-Sep-2022 | The Drew Barrymore Show | S03E06 | Lena Dunham |
| 20-Sep-2022 | The Drew Barrymore Show | S03E07 | Regina Hall; Cameron Diaz |
| 21-Sep-2022 | The Drew Barrymore Show | S03E08 | Lea Michele; Danny & Lucy DeVito |
| 22-Sep-2022 | The Drew Barrymore Show | S03E09 | Jameela Jamil |
| 23-Sep-2022 | The Drew Barrymore Show | S03E10 | John Boyega; Bill Nye |
| 26-Sep-2022 | The Drew Barrymore Show | S03E11 | Tyler Perry; Gary Vaynerchuk |
| 27-Sep-2022 | The Drew Barrymore Show | S03E12 | Susan Sarandon; Zanna Roberts Rassi |
| 28-Sep-2022 | The Drew Barrymore Show | S03E13 | Serena Williams |
| 29-Sep-2022 | The Drew Barrymore Show | S03E14 | Nick Kroll; Fat Joe; Jurnee Smollett |
| 30-Sep-2022 | The Drew Barrymore Show | S03E15 | Billy Eichner, Luke Macfarlane, Guy Branum, and the Cast of "Bros" |
| 03-Oct-2022 | The Drew Barrymore Show | S03E16 | Nicole Richie; Gayle King, Tony Dokoupil, Nate Burleson |
| 04-Oct-2022 | The Drew Barrymore Show | S03E17 | Jon Hamm; Bobby Moynihan |
| 05-Oct-2022 | The Drew Barrymore Show | S03E18 | The D'Amelio Family |
| 06-Oct-2022 | The Drew Barrymore Show | S03E19 | Queen Latifah |
| 07-Oct-2022 | The Drew Barrymore Show | S03E20 | Hilary Swank; Utkarsh Ambudkar |
| 10-Oct-2022 | The Drew Barrymore Show | S03E21 | Jenny Mollen; Tamera Mowry-Housley |
| 11-Oct-2022 | The Drew Barrymore Show | S03E22 | Naomi Watts; Jacob Batalon |
| 12-Oct-2022 | The Drew Barrymore Show | S03E23 | Constance Wu |
| 13-Oct-2022 | The Drew Barrymore Show | S03E24 | Michael Strahan |
| 14-Oct-2022 | The Drew Barrymore Show | S03E25 | Jamie Lee Curtis |
| 17-Oct-2022 | The Drew Barrymore Show | S03E26 | Michelle Obama; Zooey Deschanel; Antoni Porowski |
| 18-Oct-2022 | The Drew Barrymore Show | S03E27 | Camila Cabello |
| 19-Oct-2022 | The Drew Barrymore Show | S03E28 | John Stamos |
| 20-Oct-2022 | The Drew Barrymore Show | S03E29 | Ralph Macchio; Molly Yeh |
| 21-Oct-2022 | The Drew Barrymore Show | S03E30 | George Clooney |
| 24-Oct-2022 | The Drew Barrymore Show | S03E31 | Jennette McCurdy; Celeste Barber |
| 25-Oct-2022 | The Drew Barrymore Show | S03E32 | Martha Stewart |
| 26-Oct-2022 | The Drew Barrymore Show | S03E33 | Abbi Jacobson |
| 27-Oct-2022 | The Drew Barrymore Show | S03E34 | Mikel Welch |
| 28-Oct-2022 | The Drew Barrymore Show | S03E35 | Victoria Beckham |
| 31-Oct-2022 | The Drew Barrymore Show | S03E36 | Henry Thomas, Dee Wallace, Robert MacNaughton |
| 01-Nov-2022 | The Drew Barrymore Show | S03E37 | Meghan Trainor, Chris Olsen, Peter Billingsley, Millie Peartree |
| 02-Nov-2022 | The Drew Barrymore Show | S03E38 | Gwen Stefani |
| 03-Nov-2022 | The Drew Barrymore Show | S03E39 | Elizabeth Banks, Law Roach |
| 04-Nov-2022 | The Drew Barrymore Show | S03E40 | Daniel Radcliffe, Lake Bell, Pilar Valdes, Samah Dada |
| 07-Nov-2022 | The Drew Barrymore Show | S03E41 | Millie Bobby Brown |
| 08-Nov-2022 | The Drew Barrymore Show | S03E42 | Pete Buttigieg |
| 09-Nov-2022 | The Drew Barrymore Show | S03E43 | Weird Al Yankovic, Fortune Feimster |
| 10-Nov-2022 | The Drew Barrymore Show | S03E44 | Joanna Gaines, The Cast of The Sex Lives of College Girls |
| 11-Nov-2022 | The Drew Barrymore Show | S03E45 | Ben Platt, Cole Hauser |
| 14-Nov-2022 | The Drew Barrymore Show | S03E46 | 50 Cent; Melissa Villaseñor; Ziwe |
| 15-Nov-2022 | The Drew Barrymore Show | S03E47 | Lindsay Lohan, Ali Lohan |
| 16-Nov-2022 | The Drew Barrymore Show | S03E48 | Ina Garten, Zosia Mamet |
| 17-Nov-2022 | The Drew Barrymore Show | S03E49 | Anya Taylor-Joy, Joe Buck |
| 18-Nov-2022 | The Drew Barrymore Show | S03E50 | Gayle King, Meena Harris |
| 21-Nov-2022 | The Drew Barrymore Show | S03E51 | Queen Latifah, Chris Appleton |
| 22-Nov-2022 | The Drew Barrymore Show | S03E52 | Brooke Shields, Carla Hall |
| 28-Nov-2022 | The Drew Barrymore Show | S03E53 | David Duchovny, Kirby Howell-Baptiste |
| 29-Nov-2022 | The Drew Barrymore Show | S03E54 | Jessica Biel, Fat Joe, Natasha Leggero, Erica Domesek |
| 30-Nov-2022 | The Drew Barrymore Show | S03E55 | Cameron Diaz, Tiki Barber, Anne Burrell |
| 01-Dec-2022 | The Drew Barrymore Show | S03E56 | Whoopi Goldberg, Matt Rogers |
| 02-Dec-2022 | The Drew Barrymore Show | S03E57 | Katherine Heigl |
| 05-Dec-2022 | The Drew Barrymore Show | S03E58 | Kristina Zias |
| 06-Dec-2022 | The Drew Barrymore Show | S03E59 | Adam Sandler |
| 07-Dec-2022 | The Drew Barrymore Show | S03E60 | Mindy Kaling |
| 08-Dec-2022 | The Drew Barrymore Show | S03E61 | Janelle James, Mike Birbiglia, Eitan Bernath |
| 09-Dec-2022 | The Drew Barrymore Show | S03E62 | Zoey Deutch, Jim Parsons, Ben Aldridge, Gayle King |
| 12-Dec-2022 | The Drew Barrymore Show | S03E63 | Meghan Trainor, Richard Fierro |
| 13-Dec-2022 | The Drew Barrymore Show | S03E64 | Ellen Pompeo, Meghan Trainor, Chef Sheri Jefferson |
| 14-Dec-2022 | The Drew Barrymore Show | S03E65 | Jesse Williams, Sara Jane Ho |
| 15-Dec-2022 | The Drew Barrymore Show | S03E66 | Aubrey Plaza, Savannah Guthrie, Gabe Labelle, Chef Melissa King |
| 16-Dec-2022 | The Drew Barrymore Show | S03E67 | Lily Collins, Philippine Leroy-Beaulieu, Lucas Bravo, Ashley Park, Camille Razat, Samuel Arnold, Bru |
| 19-Dec-2022 | The Drew Barrymore Show | S03E68 | President Joe Biden & Dr. Jill Biden |
| 02-Jan-2023 | The Drew Barrymore Show | S03E69 | James Corden, Julia Collin Davison, Dan Souza, Elle Simone Scott |
| 03-Jan-2023 | The Drew Barrymore Show | S03E70 | Zanna Roberts Rassi, Pilar Valdes |
| 04-Jan-2023 | The Drew Barrymore Show | S03E71 | Joe Isidori, Legacy Jackson, Kristina Zias |
| 05-Jan-2023 | The Drew Barrymore Show | S03E72 | Kate Hudson, Julie Tremaine, Brendan Kirby |
| 09-Jan-2023 | The Drew Barrymore Show | S03E73 | Stacey Abrams, José Andrés |
| 10-Jan-2023 | The Drew Barrymore Show | S03E74 | Deborah Norville |
| 11-Jan-2023 | The Drew Barrymore Show | S03E75 | RuPaul Charles, Anne Burrell |
| 12-Jan-2023 | The Drew Barrymore Show | S03E76 | Gerard Butler |
| 13-Jan-2023 | The Drew Barrymore Show | S03E77 | Property Brothers |
| 16-Jan-2023 | The Drew Barrymore Show | S03E78 | Tracee Ellis Ross, Dawn Russell |
| 17-Jan-2023 | The Drew Barrymore Show | S03E79 | Brendan Fraser, Mikel Welch, Katie Sturino |
| 18-Jan-2023 | The Drew Barrymore Show | S03E80 | Chelsea Handler, Pinky Cole |
| 19-Jan-2023 | The Drew Barrymore Show | S03E81 | Jesse Eisenberg, Finn Wolfhard, Sophia Roe |
| 20-Jan-2023 | The Drew Barrymore Show | S03E82 | Yara Shahidi |
| 23-Jan-2023 | The Drew Barrymore Show | S03E83 | Sam Smith, Michael Griffin, Brian Orakpo, Bryan Hynson |
| 24-Jan-2023 | The Drew Barrymore Show | S03E84 | Julie Bowen |
| 25-Jan-2023 | The Drew Barrymore Show | S03E85 | Allison Williams, Aisha Tyler, Danny Seo |
| 26-Jan-2023 | The Drew Barrymore Show | S03E86 | Josh Duhamel, Thomas Doherty |
| 27-Jan-2023 | The Drew Barrymore Show | S03E87 | Nia Long, Lauren London |
| 30-Jan-2023 | The Drew Barrymore Show | S03E88 | Natasha Lyonne, Lisa Guerrero, Remi Cruz, Dionne Forest |
| 31-Jan-2023 | The Drew Barrymore Show | S03E89 | Taylor Schilling, Wolfgang Puck |
| 01-Feb-2023 | The Drew Barrymore Show | S03E90 | Gabrielle Union, Samara Joy, Chef Melba Wilson |
| 02-Feb-2023 | The Drew Barrymore Show | S03E91 | Rita Ora, Dr. Suzanne Gilberg-Lenz |
| 03-Feb-2023 | The Drew Barrymore Show | S03E92 | Jay Shetty |
| 06-Feb-2023 | The Drew Barrymore Show | S03E93 | Tyler Posey, Daymond John |
| 07-Feb-2023 | The Drew Barrymore Show | S03E94 | Alan Cumming, Ari Notartomaso, Cheyenne Isabel Wells, Marisa Davila, Tricia Fukuhara |
| 08-Feb-2023 | The Drew Barrymore Show | S03E95 | Teresa Giudice, Adam Pally |
| 09-Feb-2023 | The Drew Barrymore Show | S03E96 | Alison Brie, Diego Boneta |
| 10-Feb-2023 | The Drew Barrymore Show | S03E97 | Pamela Anderson, Katherine Schwarzenegger Pratt |
| 13-Feb-2023 | The Drew Barrymore Show | S03E98 | Jamie Oliver, Mikel Welch |
| 14-Feb-2023 | The Drew Barrymore Show | S03E99 | Reese Witherspoon, Rayna Greenberg, Ashley Hesseltin |
| 15-Feb-2023 | The Drew Barrymore Show | S03E100 | Meagan Good, Brie Bella, Nikki Bella, Chris Appleton |
| 16-Feb-2023 | The Drew Barrymore Show | S03E101 | Tori Spelling, Jennie Garth, D'Arcy Carden |
| 17-Feb-2023 | The Drew Barrymore Show | S03E102 | Kristin Chenoweth, David Chang |
| 20-Feb-2023 | The Drew Barrymore Show | S03E103 | Tig Notaro |
| 21-Feb-2023 | The Drew Barrymore Show | S03E104 | William Jackson Harper, Andrew Rea |
| 22-Feb-2023 | The Drew Barrymore Show | S03E105 | Penn Badgley, John Oliver, Rachel Dratch |
| 23-Feb-2023 | The Drew Barrymore Show | S03E106 | Sen. Bernie Sanders, Jabari Banks |
| 24-Feb-2023 | The Drew Barrymore Show | S03E107 | Guy Fieri, Taye Diggs |
| 27-Feb-2023 | The Drew Barrymore Show | S03E108 | P!NK |
| 28-Feb-2023 | The Drew Barrymore Show | S03E109 | Gayle King, Nat Wolff |
| 01-Mar-2023 | The Drew Barrymore Show | S03E110 | Whitney Cummings, Patricia Field |
| 02-Mar-2023 | The Drew Barrymore Show | S03E111 | Rebel Wilson, Lauren Makk, Garcelle Beauvais, Eliza VanCort |
| 03-Mar-2023 | The Drew Barrymore Show | S03E112 | Bobby Farrelly, Madison Telvin, Kevin Iannucci, Joshua Felder |
| 06-Mar-2023 | The Drew Barrymore Show | S03E113 | Tan France, Gigi Hadid |
| 07-Mar-2023 | The Drew Barrymore Show | S03E114 | Christine Taylor |
| 08-Mar-2023 | The Drew Barrymore Show | S03E115 | Riley Keough, Sam Claflin, Camila Morrone, Josh Whitehouse, Suki Waterhouse, Sebastion Chacon |
| 09-Mar-2023 | The Drew Barrymore Show | S03E116 | Sheryl Underwood |
| 10-Mar-2023 | The Drew Barrymore Show | S03E117 | Melissa Rivers, Law Roach, Kevin Frazier, Nischelle Turner, Wolfgang Puck |
| 13-Mar-2023 | The Drew Barrymore Show | S03E118 | Eva Longoria, Damson Idris, Dylan Mulvaney |
| 14-Mar-2023 | The Drew Barrymore Show | S03E119 | Courteney Cox, Melissa Barrera, Tony Dokoupil, Tamar Adler |
| 15-Mar-2023 | The Drew Barrymore Show | S03E120 | Kerry Washington |
| 16-Mar-2023 | The Drew Barrymore Show | S03E121 | Paris Hilton, Ronnie Woo |
| 17-Mar-2023 | The Drew Barrymore Show | S03E122 | Keira Knightley, Carrie Coon, Justice Smith, Ali Landry |
| 20-Mar-2023 | The Drew Barrymore Show | S03E123 | Nate Berkus, Jeremiah Brent, Brandon Marshall |
| 21-Mar-2023 | The Drew Barrymore Show | S03E124 | Lucy Liu, Rob Riggle, Dan Pelosi |
| 22-Mar-2023 | The Drew Barrymore Show | S03E125 | The Talk Hosts |
| 23-Mar-2023 | The Drew Barrymore Show | S03E126 | Jane Fonda, Lily Tomlin, Ike Barinholtz, Ally Love |
| 24-Mar-2023 | The Drew Barrymore Show | S03E127 | Theresa Caputo, Mario Cantone |
| 27-Mar-2023 | The Drew Barrymore Show | S03E128 | Adam Sandler, Jennifer Aniston, Peyton List |
| 28-Mar-2023 | The Drew Barrymore Show | S03E129 | Melanie Lynskey, Dougray Scott |
| 29-Mar-2023 | The Drew Barrymore Show | S03E130 | Zach Braff, Ally Love, Melanie Lynskey |
| 30-Mar-2023 | The Drew Barrymore Show | S03E131 | Lionel Richie, Sarah Sherman |
| 31-Mar-2023 | The Drew Barrymore Show | S03E132 | John Legend, Tabitha Brown |
| 03-Apr-2023 | The Drew Barrymore Show | S03E133 | Mary J. Blige, Remy Ma |
| 04-Apr-2023 | The Drew Barrymore Show | S03E134 | Chris Pratt, Brandon Marshall |
| 05-Apr-2023 | The Drew Barrymore Show | S03E135 | Keegan-Michael Key, Chris Appleton, Suzanne Somers |
| 06-Apr-2023 | The Drew Barrymore Show | S03E136 | Rob Lowe, John Owen Lowe, Christine Ko |
| 07-Apr-2023 | The Drew Barrymore Show | S03E137 | Tituss Burgess, Katie Sturino |
| 10-Apr-2023 | The Drew Barrymore Show | S03E138 | Cedric The Entertainer, Emily Hampshire |
| 11-Apr-2023 | The Drew Barrymore Show | S03E139 | Brooke Shields, Ali Wentworth, Jordan Fisher |
| 12-Apr-2023 | The Drew Barrymore Show | S03E140 | Chloe Bailey, Danny Seo |
| 13-Apr-2023 | The Drew Barrymore Show | S03E141 | Kathryn Hahn, Ramon Rodriguez |
| 14-Apr-2023 | The Drew Barrymore Show | S03E142 | Toni Collette, Nicholas Hoult |
| 17-Apr-2023 | The Drew Barrymore Show | S03E143 | Jennifer Garner |
| 18-Apr-2023 | The Drew Barrymore Show | S03E144 | Lisa Ann Walter, Alex Edelman, Druski |
| 19-Apr-2023 | The Drew Barrymore Show | S03E145 | Katie Holmes, Justin Sylvester, Lucy Freyer |
| 20-Apr-2023 | The Drew Barrymore Show | S03E146 | Jim Gaffigan |
| 21-Apr-2023 | The Drew Barrymore Show | S03E147 | Ben Affleck, Neil deGrasse Tyson |
| 24-Apr-2023 | The Drew Barrymore Show | S03E148 | Michelle Obama |
| 25-Apr-2023 | The Drew Barrymore Show | S03E149 | Helen Mirren |
| 26-Apr-2023 | The Drew Barrymore Show | S03E150 | Rainn Wilson, Brooke Shields, Ali Wentworth, Madison Beer |
| 27-Apr-2023 | The Drew Barrymore Show | S03E151 | Danny Seo, Zanna Roberts Rassi |
| 01-May-2023 | The Drew Barrymore Show | S03E152 | Pilar Valdes |
| 02-May-2023 | The Drew Barrymore Show | S03E153 | Tiki Barber, Anne Burrell |
| 03-May-2023 | The Drew Barrymore Show | S03E154 | Dove Cameron |
| 08-May-2023 | The Drew Barrymore Show | S03E155 | Vanessa Hudgens |
| 09-May-2023 | The Drew Barrymore Show | S03E156 | Ben Napier, Erin Napier, Brandon Marshall, Chasten Buttigieg |
| 10-May-2023 | The Drew Barrymore Show | S03E157 | Mindy Kaling |
| 11-May-2023 | The Drew Barrymore Show | S03E158 | Kate Bosworth, Echo Kellum |
| Season 4 | |||
| 16-Oct-2023 | The Drew Barrymore Show | S04E01 | Season 4 Premiere |
| 17-Oct-2023 | The Drew Barrymore Show | S04E02 | Dr. Suzanne Gilberg-Lenz, Pilar Valdes |
| 18-Oct-2023 | The Drew Barrymore Show | S04E03 | Julia Fox, Eitan Bernath |
| 19-Oct-2023 | The Drew Barrymore Show | S04E04 | Bob Odenkirk, Erin Odenkirk Chris, Appleton |
| 20-Oct-2023 | The Drew Barrymore Show | S04E05 | Dr. Suzanne Gilberg-Lenz, Chris Appleton |
| 23-Oct-2023 | The Drew Barrymore Show | S04E06 | Gwyneth Paltrow, Nicole Avant |
| 24-Oct-2023 | The Drew Barrymore Show | S04E07 | Cleo Wade, Danny Seo |
| 25-Oct-2023 | The Drew Barrymore Show | S04E08 | Reggie Watts, Yara Shahidi |
| 26-Oct-2023 | The Drew Barrymore Show | S04E09 | Mikel Welch, Barbara Costello |
| 27-Oct-2023 | The Drew Barrymore Show | S04E10 | John Stamos, Giada De Laurentiis |
| 30-Oct-2023 | The Drew Barrymore Show | S04E11 | Theresa Caputo, Bobby Berk |
| 31-Oct-2023 | The Drew Barrymore Show | S04E12 | Ree Drummond, Chris Appleton, Danny Seo |
| 01-Nov-2023 | The Drew Barrymore Show | S04E13 | Daymond John, Pilar Valdes |
| 02-Nov-2023 | The Drew Barrymore Show | S04E14 | Dylan Marron, Sarah Cooper, Dan Churchill |
| 03-Nov-2023 | The Drew Barrymore Show | S04E15 | Pauly Shore, Hannah Berner |
| 06-Nov-2023 | The Drew Barrymore Show | S04E16 | Keegan-Michael Key, Danny Seo |
| 07-Nov-2023 | The Drew Barrymore Show | S04E17 | Josh Gad, Krystal Joy Brown, Erin French |
| 08-Nov-2023 | The Drew Barrymore Show | S04E18 | Tallulah Willis |
| 09-Nov-2023 | The Drew Barrymore Show | S04E19 | Geri Halliwell-Horner |
| 10-Nov-2023 | The Drew Barrymore Show | S04E20 | Megan Fox |
| 13-Nov-2023 | The Drew Barrymore Show | S04E21 | Hilary Duff, Michael Urie |
| 14-Nov-2023 | The Drew Barrymore Show | S04E22 | Gabrielle Union |
| 15-Nov-2023 | The Drew Barrymore Show | S04E23 | Joel Madden, Steve-O |
| 16-Nov-2023 | The Drew Barrymore Show | S04E24 | Christian Horner |
| 17-Nov-2023 | The Drew Barrymore Show | S04E25 | Dr. Suzanne Gilberg-Lenz |
| 20-Nov-2023 | The Drew Barrymore Show | S04E26 | Gayle King, Tony Dokoupil, Nate Burleson, Jasmine Roth |
| 21-Nov-2023 | The Drew Barrymore Show | S04E27 | Andrew Rannells, Pilar Valdes, Mikel Welch |
| 22-Nov-2023 | The Drew Barrymore Show | S04E28 | Lisa Ling, Eric André, Dan Curry |
| 27-Nov-2023 | The Drew Barrymore Show | S04E29 | Dolly Parton |
| 28-Nov-2023 | The Drew Barrymore Show | S04E30 | Jada Pinkett Smith |
| 29-Nov-2023 | The Drew Barrymore Show | S04E31 | Kerry Washington, Delaney Rowe |
| 30-Nov-2023 | The Drew Barrymore Show | S04E32 | Ariana DeBose, Delilah |
| 01-Dec-2023 | The Drew Barrymore Show | S04E33 | Anne Hathaway, Fabrizio Villalpando, Eitan Bernath, Danny Seo |
| 04-Dec-2023 | The Drew Barrymore Show | S04E34 | Headlines |
| 05-Dec-2023 | The Drew Barrymore Show | S04E35 | Natalie Portman |
| 06-Dec-2023 | The Drew Barrymore Show | S04E36 | Sebastian Maniscalco Ben & Erin Napier |
| 07-Dec-2023 | The Drew Barrymore Show | S04E37 | Michelle Pfeiffer, Pilar Valdes |
| 08-Dec-2023 | The Drew Barrymore Show | S04E38 | Martha Stewart, Mark Rober |
| 11-Dec-2023 | The Drew Barrymore Show | S04E39 | Timothée Chalamet, Hugh Grant, Keegan-Michael Key |
| 12-Dec-2023 | The Drew Barrymore Show | S04E40 | Oprah Winfrey, Mikel Welch |
| 13-Dec-2023 | The Drew Barrymore Show | S04E41 | Matt Bomer, Jonathan Bailey, Allison Williams, Jelani Alladin, Noah Ricketts |
| 14-Dec-2023 | The Drew Barrymore Show | S04E42 | Gary Oldman, Pilar Valdes, Mikel Welch, Danny Seo |
| 20-Dec-2023 | The Drew Barrymore Show | S04E43 | Jason Momoa, Gracie Abrams, Anne Burrell, Danny Seo |
| 21-Dec-2023 | The Drew Barrymore Show | S04E44 | Glen Powell, Sydney Sweeney |
| 08-Jan-2024 | The Drew Barrymore Show | S04E45 | Tim Griffin, Mekialaya White |
| 09-Jan-2024 | The Drew Barrymore Show | S04E46 | Joshua Weissman |
| 10-Jan-2024 | The Drew Barrymore Show | S04E47 | Dan Souza, Zanna Roberts, Rassi Mikel Welch |
| 11-Jan-2024 | The Drew Barrymore Show | S04E48 | Billy Porter |
| 12-Jan-2024 | The Drew Barrymore Show | S04E49 | Reneé Rapp |
| 15-Jan-2024 | The Drew Barrymore Show | S04E50 | Tony Dokoupil, Nate Burleson, Lamorne Morris |
| 16-Jan-2024 | The Drew Barrymore Show | S04E51 | Annette Bening |
| 17-Jan-2024 | The Drew Barrymore Show | S04E52 | Dan Levy, Hetty McKinnon |
| 18-Jan-2024 | The Drew Barrymore Show | S04E53 | Lucy Hale, Nat Wolff, Mikel Welch |
| 19-Jan-2024 | The Drew Barrymore Show | S04E54 | Clive Owen, Stefanie Wilder-Taylor, Melissa Ben-Ishay |
| 22-Jan-2024 | The Drew Barrymore Show | S04E55 | Isla Fisher, Ashleigh Banfield |
| 23-Jan-2024 | The Drew Barrymore Show | S04E56 | Barry Manilow, Bruce Sussman, Dr. Aliza Pressman |
| 24-Jan-2024 | The Drew Barrymore Show | S04E57 | Andie MacDowell, Theresa Caputo |
| 25-Jan-2024 | The Drew Barrymore Show | S04E58 | Andie MacDowell, Dermot Mulroney, Mary Stuart Masterson |
| 26-Jan-2024 | The Drew Barrymore Show | S04E59 | Erika Alexander, Jacqueline Novak |
| 29-Jan-2024 | The Drew Barrymore Show | S04E60 | Chef Jamie Oliver |
| 30-Jan-2024 | The Drew Barrymore Show | S04E61 | Chrissy Teigen, Dave Karger |
| 31-Jan-2024 | The Drew Barrymore Show | S04E62 | Austin Butler, Callum Turner, Sharon Brous |
| 01-Feb-2024 | The Drew Barrymore Show | S04E63 | Zanna Roberts Rassi |
| 02-Feb-2024 | The Drew Barrymore Show | S04E64 | Mario Carbone |
| 05-Feb-2024 | The Drew Barrymore Show | S04E65 | Bryce Dallas Howard, Tabitha Brown, Wilson Tang |
| 06-Feb-2024 | The Drew Barrymore Show | S04E66 | Demi Moore, Naomi Watts, Diane Lane, Chloë Sevigny, Molly Ringwald, Calista Flockhart |
| 07-Feb-2024 | The Drew Barrymore Show | S04E67 | Sam Rockwell |
| 08-Feb-2024 | The Drew Barrymore Show | S04E68 | Boomer Esiason, Tiki Barber |
| 09-Feb-2024 | The Drew Barrymore Show | S04E69 | Victor Cruz, Tiki Barber |
| 12-Feb-2024 | The Drew Barrymore Show | S04E70 | Maddie Ziegler, Carla Hall |
| 13-Feb-2024 | The Drew Barrymore Show | S04E71 | Cole Sprouse, Kathryn Newton, Diablo Cody, Zelda Williams |
| 14-Feb-2024 | The Drew Barrymore Show | S04E72 | Demi Lovato, Pilar Valdes |
| 15-Feb-2024 | The Drew Barrymore Show | S04E73 | Maisie Williams, Dr. Suzanne Gilberg-Lenz |
| 16-Feb-2024 | The Drew Barrymore Show | S04E74 | Annaleigh Ashford, Rachel Smith |
| 19-Feb-2024 | The Drew Barrymore Show | S04E75 | Amanda Gorman, Camila Mendes, Chris Appleton |
| 20-Feb-2024 | The Drew Barrymore Show | S04E76 | Savannah Guthrie, Liza Koshy, Ghetto Gastro |
| 21-Feb-2024 | The Drew Barrymore Show | S04E77 | Queen Latifah, Kelly Rowland |
| 22-Feb-2024 | The Drew Barrymore Show | S04E78 | Drew's Birthday Surprise Show |
| 23-Feb-2024 | The Drew Barrymore Show | S04E79 | Margaret Qualley, Beanie Feldstein, Geraldine Viswanathan |
| 26-Feb-2024 | The Drew Barrymore Show | S04E80 | Sterling K. Brown, Jenny Slate |
| 27-Feb-2024 | The Drew Barrymore Show | S04E81 | Christina Aguilera |
| 28-Feb-2024 | The Drew Barrymore Show | S04E82 | Lisa Ling, Alan Cumming, Danny Seo |
| 29-Feb-2024 | The Drew Barrymore Show | S04E83 | Boy George, Chloe Fineman |
| 01-Mar-2024 | The Drew Barrymore Show | S04E84 | Reba McEntire |
| 04-Mar-2024 | The Drew Barrymore Show | S04E85 | Robin Wright, Sabrina Elba, Radhi Devlukia-Shetty |
| 05-Mar-2024 | The Drew Barrymore Show | S04E86 | Phil & Lily Rosenthal, Erin Moriarty |
| 06-Mar-2024 | The Drew Barrymore Show | S04E87 | Kyle Richards, Melissa Gorga, Gizelle Bryant, Dorinda Medley, Ashley Darby |
| 07-Mar-2024 | The Drew Barrymore Show | S04E88 | Millie Bobby Brown, Jack Antonoff |
| 08-Mar-2024 | The Drew Barrymore Show | S04E89 | Nischelle Turner, Kevin Frazier, Zanna Roberts Rassi, Pilar Valdes |
| 11-Mar-2024 | The Drew Barrymore Show | S04E90 | Girls5eva, Rachel Smith |
| 12-Mar-2024 | The Drew Barrymore Show | S04E91 | John Cena, Ashley Graham |
| 13-Mar-2024 | The Drew Barrymore Show | S04E92 | Dwayne "The Rock" Johnson, Jeremy Ford |
| 14-Mar-2024 | The Drew Barrymore Show | S04E93 | Lindsay Lohan, Nicole Byer, Dr. Suzanne Gilberg-Lenz |
| 15-Mar-2024 | The Drew Barrymore Show | S04E94 | Awkwafina, Jake Lacy |
| 18-Mar-2024 | The Drew Barrymore Show | S04E95 | Kristen Stewart |
| 19-Mar-2024 | The Drew Barrymore Show | S04E96 | Pilar Valdes |
| 20-Mar-2024 | The Drew Barrymore Show | S04E97 | Marie Osmond, Eitan Bernath |
| 21-Mar-2024 | The Drew Barrymore Show | S04E98 | Simu Liu, Deborah Norville |
| 22-Mar-2024 | The Drew Barrymore Show | S04E99 | Molly Baz |
| 25-Mar-2024 | The Drew Barrymore Show | S04E100 | Zanna Roberts Rassi |
| 26-Mar-2024 | The Drew Barrymore Show | S04E101 | Carla Gugino, Hoda Kotb |
| 27-Mar-2024 | The Drew Barrymore Show | S04E102 | Sydney Sweeney |
| 28-Mar-2024 | The Drew Barrymore Show | S04E103 | Mel B, Dr. Suzanne Gilberg-Lenz |
| 29-Mar-2024 | The Drew Barrymore Show | S04E104 | Eugene Levy |
| 01-Apr-2024 | The Drew Barrymore Show | S04E105 | Maya Rudolph, Victoria Garrick Browne |
| 02-Apr-2024 | The Drew Barrymore Show | S04E106 | Eiza González, Tony Dokoupil |
| 03-Apr-2024 | The Drew Barrymore Show | S04E107 | Zoe Saldana, Lisa Whelchel |
| 04-Apr-2024 | The Drew Barrymore Show | S04E108 | Jessica Capshaw, Aly Raisman |
| 05-Apr-2024 | The Drew Barrymore Show | S04E109 | Jenna Dewan, Guy Fieri |
| 08-Apr-2024 | The Drew Barrymore Show | S04E110 | Joey King, Logan Lerman |
| 09-Apr-2024 | The Drew Barrymore Show | S04E111 | Jerrod Carmichael, Carrie Preston, Zanna Roberts Rassi |
| 10-Apr-2024 | The Drew Barrymore Show | S04E112 | Sofia Boutella, Eitan Bernath |
| 11-Apr-2024 | The Drew Barrymore Show | S04E113 | Chef Eric Ripert |
| 12-Apr-2024 | The Drew Barrymore Show | S04E114 | Wilmer Valderrama |
| 15-Apr-2024 | The Drew Barrymore Show | S04E115 | Valerie Bertinelli |
| 16-Apr-2024 | The Drew Barrymore Show | S04E116 | Kristina Zias |
| 17-Apr-2024 | The Drew Barrymore Show | S04E117 | Nicole Richie |
| 18-Apr-2024 | The Drew Barrymore Show | S04E118 | Kristina Zias I |
| 19-Apr-2024 | The Drew Barrymore Show | S04E119 | Christine Taylor, David Lascher |
| 22-Apr-2024 | The Drew Barrymore Show | S04E120 | Cristina Ferrare, Danny Seo |
| 23-Apr-2024 | The Drew Barrymore Show | S04E121 | Donnie Wahlberg, Bridget Moynahan, Deborah Norville |
| 24-Apr-2024 | The Drew Barrymore Show | S04E122 | Tony Dokoupil, Nate Burleson, Zanna Roberts Rassi |
| 25-Apr-2024 | The Drew Barrymore Show | S04E123 | Arthur Brooks |
| 26-Apr-2024 | The Drew Barrymore Show | S04E124 | Janet Jackson, Matthew Hussey |
| 29-Apr-2024 | The Drew Barrymore Show | S04E125 | Vice President Kamala Harris |
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